Dr. Bruce Banner (Edward Norton) desperately searching for a cure to the gamma radiation which has poisoned his cells and unleashed a primal force of rage within him known as The Hulk. Living in the shadows and cut off from a life with the woman he loves, Dr. Betty Ross (Liv Tyler), Bruce knows that a military machine led by General "Thunderbolt" Ross (William Hurt) is seeking to capture and brutally exploit his power.
As all three grapple with the secrets that led to The Hulk's creation, they are confronted with a vicious new enemy known as The Abomination — a monstrosity whose destructive strength exceeds even that of The Hulk's. To defeat this nemesis, the film's hero must make an agonizing choice: accept a peaceful life as Bruce Banner or find heroism in the creature he holds inside.